Source: http://calendar.nih.gov/app/MCalInfoView.aspx?evtID=25534
Thursday 16 August 2012
Introduction to Making MS Office 2010 Documents 508 Compliant
Date: Wednesday, 08 29, 2012; Speaker: Linda Haynes-Jackson, CIT; Biomedical Research Center (BRC) - Baltimore, MD; 04A315
NIH Library Resource Training - Sequence Similarity Search: BLAT
Date: Thursday, 08 23, 2012; Speaker: BLAT; Building: Building 10 (Clinical Center); NIH Library Training Room
Source: http://calendar.nih.gov/app/MCalInfoView.aspx?evtID=25568
Cameron Richardson Camilla Belle Carla Campbell Carla Gugino Carmen Electra
National Advisory Eye Council Welcomes Four New Members
The National Advisory Eye Council for the National Eye Institute (NEI), part of the National Institutes of Health, announces the appointment of four new members: Joseph A. Bonanno, O.D., Ph.D.; James Chodosh, M.D., M.P.H.; Col. Donald A. Gagliano, M.D.; and Alberta L. Orr, M.S.W.
Source: http://www.nei.nih.gov/news/pressreleases/080309.asp?nav=rss
Daniella Alonso Danneel Harris Deanna Russo Denise Richards Desiree Dymond
Wednesday 15 August 2012
Neurotoxicity
Neurotoxicity information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: http://www.ninds.nih.gov/disorders/neurotoxicity/neurotoxicity.htm
Catherine Bell Chandra West Charisma Carpenter Charli Baltimore Charlies Angels
Transplant and Autoimmune Therapy Using T-Cells Expressing Programmed Death Ligand-1 (PD-L1)
Transplant complications (graft rejection and graft-versus-host disease) and autoimmune diseases are primarily caused by T cell immune responses against normal host tissue or transplanted tissues. These disorders can lead to serious complications and may be chronic, debilitating, and fatal. Current treatment for these disorders is oftentimes not effective, and is typically associated with significant side effects, including global immune suppression, which increases the rate of infection and cancer. Hence, there is a need for new technologies to more specifically suppress the immune system for treatment of these diseases.
Programmed death (PD) ligand 1 (PD-L1) is an immune molecule present on regulatory T cells (Tregs), other suppressor cell populations, and tumor cells; the function of PD-L1 is to suppress the function of pathogenic T cells that express the PD1 receptor. Therefore, it has been hypothesized that the transfer of T cells that are enriched for PD-L1 expression might represent an effective method to suppress autoimmunity or transplant complications. Adoptive T cell therapy using Tregs is one such approach; however, this approach is limited due to the relative rarity of Tregs and their tendency to possess differentiation plasticity towards pathogenic T cell subsets such as the Th17 subset. Ex vivo co-stimulated and expanded effector T cells can be generated in sufficient numbers for cell therapy; however, such cells are not enriched for PD-L1 expression.
The current technology overcomes these limitations through transduction of co-stimulated T cells with a lentiviral expression vector that dictates T cell expression of PD-L1. In this method, the co-stimulated T cells acquire the immunosuppressant characteristics of Treg cells. The PD-L1 gene expression construct co-expresses a cell surface molecule (i.e., CD19 or CD34) that allows enrichment of the gene-modified T cells to high purity. Also the construct co-expresses another gene, TMPK, which acts as a safety cell fate switch because the TMPK can specifically activate the cytotoxic prodrug, AZT. By incorporation of this TMPK/AZT cell fate safety switch, the current technology will allow for PD-L1 therapeutic delivery, with subsequent elimination of the therapeutic cells in the event of toxicity. CRADA Opportunity: The Center for Cancer Research, Experimental Transplantation and Immunology Branch, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact John D. Hewes, Ph.D. at 301-435-3121 or hewesj@mail.nih.gov for more information. Click here to view the NCI collaborative opportunity announcement.
Programmed death (PD) ligand 1 (PD-L1) is an immune molecule present on regulatory T cells (Tregs), other suppressor cell populations, and tumor cells; the function of PD-L1 is to suppress the function of pathogenic T cells that express the PD1 receptor. Therefore, it has been hypothesized that the transfer of T cells that are enriched for PD-L1 expression might represent an effective method to suppress autoimmunity or transplant complications. Adoptive T cell therapy using Tregs is one such approach; however, this approach is limited due to the relative rarity of Tregs and their tendency to possess differentiation plasticity towards pathogenic T cell subsets such as the Th17 subset. Ex vivo co-stimulated and expanded effector T cells can be generated in sufficient numbers for cell therapy; however, such cells are not enriched for PD-L1 expression.
The current technology overcomes these limitations through transduction of co-stimulated T cells with a lentiviral expression vector that dictates T cell expression of PD-L1. In this method, the co-stimulated T cells acquire the immunosuppressant characteristics of Treg cells. The PD-L1 gene expression construct co-expresses a cell surface molecule (i.e., CD19 or CD34) that allows enrichment of the gene-modified T cells to high purity. Also the construct co-expresses another gene, TMPK, which acts as a safety cell fate switch because the TMPK can specifically activate the cytotoxic prodrug, AZT. By incorporation of this TMPK/AZT cell fate safety switch, the current technology will allow for PD-L1 therapeutic delivery, with subsequent elimination of the therapeutic cells in the event of toxicity. CRADA Opportunity: The Center for Cancer Research, Experimental Transplantation and Immunology Branch, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact John D. Hewes, Ph.D. at 301-435-3121 or hewesj@mail.nih.gov for more information. Click here to view the NCI collaborative opportunity announcement.
Source: http://www.ott.nih.gov/Technologies/abstractDetails.aspx?RefNo=2163
Jennifer Garner Jennifer Gimenez Jennifer Love Hewitt Jennifer Morrison Jennifer ODell
Rabbit Polyclonal Antibody to Detect a Pro-peptide Fragment of NSAID-activated Gene (NAG-1)/GDF15, a Protein Associated with Cancer
Chronic inflammation is clearly associated with an increase in the risk of cancer. Non-steroidal anti-inflammatory drugs (NSAIDs) are well documented as agents that inhibit tumor growth and with long-term use can prevent tumor development. NSAID-activated gene (NAG-1), a unique member of the TGF-beta superfamily, is highly induced by NSAIDs and numerous drugs and chemicals with anti-tumorigenic activities.
The protein product of NAG-1 is first formed into an immature peptide dimer that must be cut at a specific site before it can be secreted as a mature protein. Currently available antibodies can only detect either the immature form of NAG-1 or the secreted mature protein, but do not recognize the peptide fragment that remains when the immature dimer is cut to form the mature protein. Now available for the first time, the present new antibody recognizes this NAG-1 pro-peptide fragment. CRADA Opportunity: The NIEHS is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this antibody. For collaboration opportunities, please contact Elizabeth M. Denholm, Ph.D. at denholme@niehs.nih.gov.
The protein product of NAG-1 is first formed into an immature peptide dimer that must be cut at a specific site before it can be secreted as a mature protein. Currently available antibodies can only detect either the immature form of NAG-1 or the secreted mature protein, but do not recognize the peptide fragment that remains when the immature dimer is cut to form the mature protein. Now available for the first time, the present new antibody recognizes this NAG-1 pro-peptide fragment. CRADA Opportunity: The NIEHS is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this antibody. For collaboration opportunities, please contact Elizabeth M. Denholm, Ph.D. at denholme@niehs.nih.gov.
Source: http://www.ott.nih.gov/Technologies/abstractDetails.aspx?RefNo=2442
Statement by the Press Secretary on Key Trade Measures in H.R. 5986
Today, the President signed into law H.R. 5986, which includes key measures to bolster domestic manufacturing and strengthen our economic ties with sub-Saharan Africa and Central America. This bill also contains provisions to renew authorities under the Burma Freedom and Democracy Act. Congress passed this legislation with overwhelming bipartisan support.
This bill addresses sub-Saharan Africa’s top trade priority with the United States by extending a key provision under the African Growth and Opportunity Act (AGOA) trade preference program until September 2015. This provision, which was set to expire in the fall, will continue to allow duty-free access to the U.S. market for certain AGOA apparel exports. AGOA continues to be critical to expanding and diversifying our trade and investment relationship with Africa.
This legislation also includes technical amendments to textile and apparel provisions under the Central America – Dominican Republic – United States Free Trade Agreement (CAFTA-DR). These technical changes will have real job-supporting economic benefits for thousands of American workers in our textile and apparel industry, and will help boost economic growth in these developing regions.
Bijou Phillips Blake Lively Blu Cantrell Bonnie Jill Laflin Bridget Moynahan
Ferroelectric order in individual nanometre-scale crystals
The length scale at which phenomena such as ferroelectricity is still present is of fundamental relevance for nanoscale applications. A high-resolution transmission electron microscopy study now shows how ferroelectricity can persist in nanoparticles down to about 5 nm in diameter, pointing the way towards the ultimate size limit for ferroelectric applications.
Source: http://feeds.nature.com/~r/nmat/rss/current/~3/n5EB01mRXA8/nmat3371
Alecia Elliott Alessandra Ambrosio Alexis Bledel Ali Campoverdi Ali Larter
Statement from Paul A. Sieving, M.D., Ph.D., Director of the National Eye Institute, National Institutes of Health, during World Glaucoma Week, March 7-13, 2010
Glaucoma is one of the world's leading causes of vision loss and blindness. Vision organizations around the globe highlight this disease as a research and public health priority during World Glaucoma Week. The National Eye Institute (NEI), part of the National Institutes of Health, takes this opportunity to reaffirm its commitment to supporting research that will identify risk factors for the condition and develop treatments to preserve the sense of sight.
Source: http://www.nei.nih.gov/news/pressreleases/030310.asp?nav=rss
Christina Milian Christina Ricci Chyler Leigh Ciara Cindy Crawford
Behcet's Disease
Behcet's Disease information page compiled by NINDS.
Source: http://www.ninds.nih.gov/disorders/behcet/behcet.htm
Aubrey ODay Audrina Patridge Autumn Reeser Avril Lavigne Bali Rodriguez
Bluetooth: How to set up your Apple Wireless Keyboard
The Apple Wireless Keyboard uses Bluetooth wireless technology to provide cable-free operation so you're free to type wherever you like. Learn how to set up, pair, and unpair your Apple Wireless Keyboard.
Source: http://support.apple.com/kb/HT1809
Gina Gershon Gina Philips Giuliana DePandi Giulianna Ramirez Grace Park
APJ acts as a dual receptor in cardiac hypertrophy
Cardiac hypertrophy is initiated as an adaptive response to sustained overload but progresses pathologically as heart failure ensues. Here we report that genetic loss of APJ, a G-protein-coupled receptor, confers resistance to chronic pressure overload by markedly reducing myocardial hypertrophy and heart failure. In contrast, mice lacking apelin (the endogenous APJ ligand) remain sensitive, suggesting an apelin-independent function of APJ. Freshly isolated APJ-null cardiomyocytes exhibit an attenuated response to stretch, indicating that APJ is a mechanosensor. Activation of APJ by stretch increases cardiomyocyte cell size and induces molecular markers of hypertrophy. Whereas apelin stimulates APJ to activate Gαi and elicits a protective response, stretch signals in an APJ-dependent, G-protein-independent fashion to induce hypertrophy. Stretch-mediated hypertrophy is prevented by knockdown of β-arrestins or by pharmacological doses of apelin acting through Gαi. Taken together, our data indicate that APJ is a bifunctional receptor for both mechanical stretch and the endogenous peptide apelin. By sensing the balance between these stimuli, APJ occupies a pivotal point linking sustained overload to cardiomyocyte hypertrophy.
Source: http://feeds.nature.com/~r/nature/rss/aop/~3/mx3ENzco7cM/nature11263
Ana Paula Lemes Ananda Lewis Angela Marcello Angelina Jolie Anna Faris
Deadly Rays from Clouds
Thunderstorms give out powerful blasts of gamma rays and x-rays, shooting beams of particles—and even antimatter—into space. The atmosphere is a stranger place than we ever imagined
Source: http://dx.doi.org/10.1038/scientificamerican0812-54
Jennifer Sky Jenny McCarthy Jessica Alba Jessica Biel Jessica Cauffiel
Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disorder information page compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: http://www.ninds.nih.gov/disorders/charcot_marie_tooth/charcot_marie_tooth.htm
Ali Campoverdi Ali Larter Alice Dodd Alicia Keys Alicia Witt
Tuesday 14 August 2012
Let’s Talk: Give Us Feedback on the NIDA for Teens Web Site
NIDA is getting ready to re-do the NIDA for Teens Web site, which gives teens science-based facts about how drugs affect the brain and body so they have more info to make healthy decisions. Now we need your help to make the site the best it can be by giving us your feedback. So… What [...]
Ashley Tisdale Asia Argento Aubrey ODay Audrina Patridge Autumn Reeser
President Obama's Call with the Prime Minister of India
President Barack Obama talks on the phone with Prime Minister Manmohan Singh of India aboard Air Force One during a flight to Colorado, Aug. 8, 2012. The President called Prime Minister Singh to express condolences for victims of the attack at the gurdwara in Wisconsin, which took the lives of Indian nationals as well as Americans, and to convey the solidarity of the American people. Ben Rhodes, Deputy National Security Advisor for Strategic Communications, is seated at right. (Official White House Photo by Pete Souza)
The two leaders discussed the shooting at the Sikh temple in Oak Creek, Wisconsin, and the President expressed his condolences for the senseless attack.
According to a readout of that conversation, "Prime Minister Singh expressed his gratitude for the many messages and gestures of support from the United States, and for the prompt reaction and heroism of the local police department."
To learn more about the call, check out the full readout here.
In the United States, the American flag remain at half-staff until sunset tomorrow to honor the victims of the shooting.
Source: http://www.whitehouse.gov/blog/2012/08/09/president-obamas-call-prime-minister-india
Beyonc? Bianca Kajlich Bijou Phillips Blake Lively Blu Cantrell
How to clean Apple products
Read recommendations and guidelines for cleaning your Apple computer, iPad, iPhone, iPod, display, or peripheral device.
Source: http://support.apple.com/kb/HT3226
Connie Nielsen Cristina Dumitru Daisy Fuentes Dania Ramirez Danica Patrick
Coffin Lowry Syndrome
Coffin Lowry Syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS)
Source: http://www.ninds.nih.gov/disorders/coffin_lowry/coffin_lowry.htm
Anna Paquin AnnaLynne McCord Anne Marie Kortright April Scott Arielle Kebbel
Software for Automated Determination of Macromolecular Structure Using Cryo-electron Microscopy
Available for licensing is software for automated generation of density maps of macromolecular structures from series of 2D digital micrographs of frozen hydrated specimens collected using an electron microscope equipped with an ultra-cooled computerized stage. Series of images of biological specimens collected at different tilt angles relative to the electron beam are aligned to compensate for mechanical errors of the stage and combined to obtain 3D images (tomograms). Sub volumes containing a single macromolecular complex can be extracted from the 3D image of a protein solution, or suspension of viruses or cells. These individual sub-volumes of identical structures are aligned and averaged together to generate a density map of the macromolecular complex of interest.
CRADA Opportunity: The NCI Laboratory of Cell Biology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. For collaboration opportunities, please contact John Hewes, Ph.D. at hewesj@mail.nih.gov. Click here to view the NCI collaborative opportunity announcement.
CRADA Opportunity: The NCI Laboratory of Cell Biology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. For collaboration opportunities, please contact John Hewes, Ph.D. at hewesj@mail.nih.gov. Click here to view the NCI collaborative opportunity announcement.
Source: http://www.ott.nih.gov/Technologies/abstractDetails.aspx?RefNo=2443
Amber Arbucci Amber Brkich Amber Heard Amber Valletta America Ferrera
Mucolipidoses
Mucolipidosis information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: http://www.ninds.nih.gov/disorders/mucolipidoses/mucolipidoses.htm
Danica Patrick Daniella Alonso Danneel Harris Deanna Russo Denise Richards
Mountain Lion: About Gatekeeper
Learn about Gatekeeper in Mountain Lion.
Personalized Body Weight Management System Using Monitoring Devices and Mathematical Models of Metabolism
Attempts to manage body weight are often unsuccessful or only temporary. This is, in part, due to antiquated dieting methods that attempt to address calorie consumption while ignoring metabolic and physical changes. It is becoming clear that personalized methods to manage body weight must be developed.
Scientists at the NIH have developed new methods for prescribing and monitoring personalized weight management interventions. The system uses validated mathematical models of human metabolism to set weight management goals and predict individual body weight outcomes in the context of changing metabolic needs and calorie consumption. The system uses repeated monitoring of a patient's body weight to assess progress and provide specific feedback to the patient and health care professional. Projected outcomes and body weight goals can be revised over time along with required prescription modifications to meet the body weight goals. The system is integrated into a network of one or more devices that may additionally monitor various physiological parameters, physical activities, food intake, or other behaviors. Such an enhanced personalized weight management program has great promise in the management of obesity. CRADA Opportunity: The NIDDK Laboratory of Biological Modeling is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. For collaboration opportunities, please contact Marguerite J. Miller at 301-496-9003 or millermarg@niddk.nih.gov.
Scientists at the NIH have developed new methods for prescribing and monitoring personalized weight management interventions. The system uses validated mathematical models of human metabolism to set weight management goals and predict individual body weight outcomes in the context of changing metabolic needs and calorie consumption. The system uses repeated monitoring of a patient's body weight to assess progress and provide specific feedback to the patient and health care professional. Projected outcomes and body weight goals can be revised over time along with required prescription modifications to meet the body weight goals. The system is integrated into a network of one or more devices that may additionally monitor various physiological parameters, physical activities, food intake, or other behaviors. Such an enhanced personalized weight management program has great promise in the management of obesity. CRADA Opportunity: The NIDDK Laboratory of Biological Modeling is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. For collaboration opportunities, please contact Marguerite J. Miller at 301-496-9003 or millermarg@niddk.nih.gov.
Source: http://www.ott.nih.gov/Technologies/abstractDetails.aspx?RefNo=2386
Christina Aguilera Christina Applegate Christina DaRe Christina Milian Christina Ricci
Thursday 9 August 2012
Kirsten Dunst Drinks Beer and Cheers on Team USA
Kirsten Dunst is the latest celebrity to get in on the Olympic action in London. Last night she drank beer and cheered from the crowd while Team USA beat Australia 119-86 in the women's basketball quarterfinals. Kristen was joined by a few friends, including the very handsome Oscar Isaac. Just last month, Kirsten was with her boyfriend, Garrett Hedlund, in NYC. Garrett and Kirsten met while filming On the Road and their big-screen chemistry can be seen in the latest On the Road trailer. The film opens in the UK Oct. 12, with the London premiere scheduled for next Thursday, but there's still no official release date for the States. There is, however, another important release date on the horizon for Kirsten. She shares the big screen with Isla Fisher, Lizzy Caplan, and James Marsden in the sure-to-be-hilarious comedy Bachelorette, which hits US theaters Sept. 7 in limited release.
Source: http://feedproxy.google.com/~r/popsugar/~3/X4QRDoUT5O8/Kirsten-Dunst-Olympics-Pictures-24369228
Kate Bosworth Is Engaged To Director Michael Polish
I don’t know if anyone else is keeping up with Kate, but I’ve become a big fan recently, having seen her in two indie films that were pretty sweet. L!fe Happens came out earlier this year and While We Were Here premiered at Tribeca, and I fell in love with both femme-centered stories, and the [...]
Source: http://www.pinkisthenewblog.com/2012-08-09/kate-bosworth-is-engaged-to-director-michael-polish
Cheryl Burke China Chow Chlo?Sevigny Christina Aguilera Christina Applegate
Sofia Vergara Tells Allure - "If You Don’t' Have a Big A*s, You're Nothing!"
Sofia Vergara nabbed the cover of September's Allure, which will be available electronically on Aug. 14 and on newsstands Aug. 21. Check out a behind-the-scenes video of Sofia's shoot and more pictures from the magazine. The coveted September cover is the latest highlight of Sofia's very big year. She was ranked the highest-earning woman on TV thanks to her part on Modern Family, became engaged to boyfriend Nick Loeb, and even won our 2012 Bikini Bracket! Sofia opened up to Allure about what being sexy means to her, liking her curves, but not being into workouts. Sofia said:
- On body shape: "I don't like when the a*s gets smaller. In Latin America if you don’t' have a big a*s you're nothing."
- On a South American idea of being sexy: "The guys I know love it. You don't have to win Miss Universe, but you have to feel attractive, and you have to feel wanted. I have so many friends that are Latin, and they're not Miss Universe, but they have something, and they get more guys than the really tall, blonde, perfect model that is just standing there. So I think sexy is the attitude of you believing that you can get whatever you want."
- On not being a fan of workouts: "While I'm working out, I'm in a bad mood. I didn’t grow up in a culture of working out. You were voluptuous, that's it. That's all you needed."
Photos courtesy Carter Smith for Allure
Source: http://feedproxy.google.com/~r/popsugar/~3/lKvQa_bzXak/Sofia-Vergara-Allure-Pictures-24368359
Gina Gershon Gina Philips Giuliana DePandi Giulianna Ramirez Grace Park
Justin Bieber's Michael Jackson Connection? Michael Madsen
Bieber's 'As Long As You Love Me' offer 'took me off guard,' says Madsen, who also starred with MJ in 2001.
By Jocelyn Vena
<P><a href="http://www.mtv.com/music/artist/bieber_justin/artist.jhtml">Justin Bieber</a> tweeted that when he was looking for inspiration for his <a href="/news/articles/1690963/justin-bieber-as-long-as-you-love-me-music-video-premiere.jhtml">"As Long As You Love Me" video</a>, there was no one he wanted to <a href="/news/articles/1691049/justin-bieber-as-long-as-you-love-me-michael-jackson.jhtml">emulate more than Michael Jackson</a>.</P><P>Coincidentally, when he needed someone to play his foe in the clip, he looked no further than a guy who has some experience working with Jackson.</P><P>That man is Michael Madsen, who appeared in Jackson's 2001 gangster-themed video for "You Rock My World" off his <i>Invincible</i> album. Oddly enough, the only people that have ever really asked the hard-edged actor to appear in videos happen to be Bieber and Jackson.</P><P></p><div class="player-placeholder right" title="Michael Madsen Has A Soft Spot For Justin Bieber" id="vid:822276" width="415" height="255"></div><p></P><P>"Hardly ever [am I asked to be in videos], that was why it was kind of funny cause that doesn't usually happen," he told MTV News. "It came out of nowhere. It was the last thing in the world I expected, to be called by Justin Bieber. It was kind of funny. It took me off guard. It's not the usual thing people think of me for, but considering the role, maybe."</P><P>In <a href="/news/articles/1690932/justin-bieber-as-long-as-you-love-me-video.jhtml">the video</a>, Madsen plays a tough guy who <a href="/news/articles/1691089/justin-bieber-michael-madsen-as-long-as-you-love-me-punch.jhtml">beats up Bieber</a> after the teen ignores his request to stay away from his daughter. It was that cinematic storyline that got Madsen interested.</P><P>"I didn't want to imagine myself on a trampoline with a lollipop, so I asked for the story. I realized it was almost like a film production; and of course, I kind of figured that it might be an interesting thing to do," he said about the Anthony Mandler-directed video. "I didn't know what to expect... I was surprised... They got me a good wardrobe. That was my shirt though. I brought my own shirt; those kinds of shirts are kind of rare.</P><P>"The story is so much Shakespearian; the couple, they run off together out the window," he later continued. "It's rather like that, I thought that was interesting. And I thought the kid, he had an enormous talent and he was very gracious to my sons and was very gracious to my family."</P><P>It was actually those sons that convinced the Hawaiian-shirt-wearing "Kill Bill" star to make the video with Bieber. "Well I was surprised at first that the kid was interested in having me be part of his video," he recalled. "I went to my sons and I asked my boys, I asked my sons what they thought if I should if they thought I should do it or not. And, of course, they gently placed their hand on my shoulder and said 'Dad don't you realize who Justin Bieber is?' And I said 'Well, no, actually I didn't.' But with their blessing I decided I thought it might be interesting."</P><P><i>Do you think Michael Madsen's appearance in "As Long As You Love Me" bumps Bieber to MJ status? Let us know in the comments!</i></P><P><object width="460" height="260" type="application/x-shockwave-flash" id="embeddedPlayer" data="http://videoplayer.vevo.com/embed/embedded" style="visibility: visible;"><param name="bgcolor" value="#000000"><param name="allowFullScreen" value="true"><param name="allowScriptAccess" value="always"><param name="wmode" value="transparent"><param name="flashvars" value="playerType=embedded&videoId=USUV71201064&playlist=false&enableDomScan=true&siteSection=MTV_mtv.com&playerId=62FF0A5C-0D9E-4AC1-AF04-1D9E97EE3961&autoplay=0&endScreen=play&cc=US&cultureName=en-US&cultureIsRTL=False&sbId=14A00605-7DB5-4492-B67B-CB2093BD89DD"></object></P>
Related ArtistsJennifer Sky Jenny McCarthy Jessica Alba Jessica Biel Jessica Cauffiel
Wednesday 8 August 2012
Coldplay, Led Zeppelin Album Covers Featured On New British Stamps
Album art from Pink Floyd, Blur and David Bowie also included.
By James Montgomery
<P>On Thursday (January 7), the U.K.'s Royal Mail unveiled a series of 10 new stamps, honoring the most iconic album covers of the past 40 years.</P><P>The albums featured in the new series are the <MTVNLINK type="artist" id="515">Rolling Stones</MTVNLINK>' <i>Let It Bleed,</i> <MTVNLINK type="artist" id="993">Led Zeppelin</MTVNLINK>'s <i>IV,</i> <MTVNLINK type="artist" id="973">David Bowie</MTVNLINK>'s <i>The Rise and Fall of Ziggy Stardust and the Spiders From Mars,</i> <MTVNLINK type="artist" id="503245">Mike Oldfield</MTVNLINK>'s <i>Tubular Bells,</i> <MTVNLINK type="artist" id="977">The Clash</MTVNLINK>'s <i>London Calling,</i> <MTVNLINK type="artist" id="267">New Order</MTVNLINK>'s <i>Power, Corruption and Lies,</i> <MTVNLINK type="artist" id="758">Primal Scream</MTVNLINK>'s <i>Screamadelica,</i> <MTVNLINK type="artist" id="1118">Pink Floyd</MTVNLINK>'s <i>The Division Bell,</i> <MTVNLINK type="artist" id="1041">Blur</MTVNLINK>'s <i>Parklife</i> and — the most recent album on to make the cut — <MTVNLINK type="artist" id="1111141">Coldplay</MTVNLINK>'s <i>A Rush of Blood to the Head.</i></P><P>Meant to honor "the most potent graphic images of modern times, many of which have provided a visual soundtrack to people's lives," the series is the end result of a lengthy research process by the Royal Mail, who looked through thousands of album covers by British artists before deciding on the final list. And, during a Wednesday night BBC Radio broadcast, it was revealed that the queen herself actually approved each design.</P><P>Led Zeppelin guitarist Jimmy Page — who helped design the cover for <i>IV</i> — was on hand to celebrate the release of the stamps and recalled the mysterious nature of the album's iconic imagery.</P><P>"Almost 40 years after the album came out, nobody knows the old man who featured on the cover, nor the artist who painted him," he said. "That sort of sums up what we wanted to achieve with the album cover, which has remained both anonymous and enigmatic at the same time."</P><P>Of course, any great honor is befitting of an equally great contest, so, on the same day the stamps were made available to the general public, Coldplay decided to give one of their <i>Rush of Blood</i> stamps away. In a message on their official site, the band held a contest to send one lucky fan "a letter using a Coldplay stamp, postmarked with today's issue date."</P><P>"We visited our local post office earlier today and bought some of the Coldplay stamps," the message read. "Very nice they are too."</P>
Related Photos Related ArtistsCiara Cindy Crawford Cindy Taylor Cinthia Moura Claudette Ortiz
Chris Cornell Filling In For Robert Plant On Led Zeppelin Tour? That's News To Him
'I have not been approached to fill in for Robert Plant on the Zeppelin tour, but that isn't to say I won't be,' singer says.
By Chris Harris
<P>Former <a href="http://www.mtv.com/music/artist/soundgarden/artist.jhtml">Soundgarden</a>Soundgarden and <a href="http://www.mtv.com/music/artist/audioslave/artist.jhtml">Audioslave</a>Audioslave frontman <a href="http://www.mtv.com/music/artist/cornell_chris/artist.jhtml">Chris Cornell</a>Chris Cornell has spoken out for the first time about rumors that he's been asked to fill in for <a href="http://www.mtv.com/music/artist/plant_robert/artist.jhtml">Robert Plant</a>Robert Plant on a proposed <a href="http://www.mtv.com/music/artist/led_zeppelin/artist.jhtml">Led Zeppelin</a>Led Zeppelin reunion tour. The trek would feature original guitarist Jimmy Page, original bassist John Paul Jones and Jason Bonham taking over on drums for his late father, John Bonham.</P><P>Cornell has been mentioned — along with <a href="http://www.mtv.com/music/artist/foo_fighters/artist.jhtml">Foo Fighters</a>Foo Fighters frontman Dave Grohl, former <a href="http://www.mtv.com/music/artist/van_halen/artist.jhtml">Van Halen</a>Van Halen frontman <a href="http://www.mtv.com/music/artist/hagar_sammy/artist.jhtml">Sammy Hagar</a>Sammy Hagar, <a href="http://www.mtv.com/music/artist/white_stripes/artist.jhtml">White Stripes</a>White Stripes mastermind Jack White and <a href="http://www.mtv.com/music/artist/alter_bridge/artist.jhtml">Alter Bridge</a>Alter Bridge's Myles Kennedy — as a potential Plant fill-in. Plant has already said that he wouldn't take part in the tour.</P><P></p><div style="margin: 0px 10px 10px 0px; float: left;"> <embed src="http://media.mtvnservices.com/mgid:uma:video:mtv.com:314096" width="256" height="223" type="application/x-shockwave-flash" flashVars="configParams=instance%3Dnews%26vid%3D314096" allowFullScreen="true" allowScriptAccess="always" base="."></embed></div><p></P><P>"I have not been approached so far to fill in for Robert Plant on the upcoming Zeppelin tour, but that isn't to say I won't be," Cornell told MTV News. "I've heard that from about 200 people now, and it might be one of those situations where it's just an online rumor or it might be true. But if you see anyone from Led Zeppelin around, let me know. I think I should actually fill in for Jimmy Page on the Robert Plant/ Alison Krauss tour."</P><P>Cornell's denial comes just a day after <a href="http://www.mtv.com/music/artist/aerosmith/artist.jhtml">Aerosmith</a>Aerosmith guitarist <a href="http://aeronewsdaily.com/blog/2008/10/31/aerosmith-guitarist-says-page-trying-to-motivate-plant-to-return-to-zeppelin/" target="_blank">Brad Whitford confirmed reports</a> that frontman Steven Tyler recently met with Zeppelin for an impromptu jam session. "They did it for fun," Whitford said during an appearance on the syndicated show "Todd N Tyler Radio Empire." "I actually think Jimmy wanted Steven to come over and play a little bit because I think he was trying to light a fire under Robert."</P><P>Rumors of a Zeppelin reunion tour have abounded since the iconic band played <a href="/news/articles/1576186/led-zeppelin-give-fans-whole-lotta-love-at-reunion-show.jhtml">a single reunion set</a> last year at London's O2 Arena. <a href="http://www.mtv.com/music/artist/twisted_sister/artist.jhtml">Twisted Sister</a>Twisted Sister frontman Dee Snider added fuel to the fire last month when he revealed that the group was thinking of touring, with or without Plant.</P><P><a href="http://newsroom.mtv.com/2008/10/13/another-led-zeppelin-rumor-almost-debunked/">According to Snider</a>, the rest of the band told Plant, " 'We're all rehearsed, we're ready to go. Here's a gazillion dollars on the table. If you don't do it, we're going out with this kid [Myles Kennedy].' "</P><P>"And he can sing the sh-- out of Zeppelin," Snider added. "They're going to hope that Robert, at the last minute, will go, 'OK,' and step in."</P><P>In a recent interview, Jones told BBC Radio Devon that a new singer was being sought to take over for Plant. "We are trying out a couple of singers," he said. "We want to do it. It's sounding great, and we want to get on and get out there."</P><P>But Jones insists that he, Page and Bonham aren't interested in finding a Plant clone. "It's got to be right," he said. "There's no point in just finding another Robert. You could get that out of a tribute band, but we don't want to be our own tribute band. There would be a record and a tour, but everyone has to be onboard."</P><P>Of course, even if Zeppelin were to approach him, Cornell might be too busy to take over vocals for the band. His upcoming <a href="http://www.mtv.com/music/artist/timbaland/artist.jhtml">Timbaland</a>Timbaland-produced solo LP, <a href="/news/articles/1596730/chris-cornell-debuts-timbaland-produced-track-on-tv-show.jhtml"><i>Scream,</i></a> will be released within the next few months. Cornell told MTV News last month that some of his fans might consider <i>Scream</i> something of a departure, but he doesn't see it that way.</P><P>"It makes me happy that there's this perception that I have a group of fans that I'm now sort of throwing a curve at and what their reaction will be," he said. "But I've been in this situation so many times already. When I put out [1999's] <i>Euphoria Morning,</i> my main goal was to create an album that sounded like nothing I'd done in Soundgarden, and I did that. I also had that with Temple of the Dog, where I showed up with songs that weren't necessarily riff-based. And then, of course, the pairing of me and members of <a href="http://www.mtv.com/music/artist/rage_against_the_machine/artist.jhtml">Rage Against the Machine</a>Rage Against the Machine had everyone sort of speculating about what that would sound like.</P><P>"It feels like I've done this so many times that when it's presented to me as being a departure, I feel that's a misconception," he added. "I feel like that's my theme at this point."</P>
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Photos | Beyonce's 'Love On Top' Tease: Five Key Scenes!
Beyoncé - I Was Here (Live at Roseland)
- Artist: Beyoncé
- Label: Parkwood Entertainment/Columbia
- Director: Beyoncé Knowles
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Madonna & Lola Announce Georgia May Jagger As New Global Material Girl
MG Icon, the joint venture between Iconix Brand Group, Inc. and Madonna announced today, Georgia May Jagger, as the new global face of Material Girl. Jagger will appear in the brand’s global marketing campaigns. Georgia May Jagger joins past Material Girls, Kelly Osbourne and Taylor Momsen to be selected by Madonna and Lola to appear [...]
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Karmin Invite You To Their 'Coming-Out Party' In 'Hello' Video
Karmin's Amy Heidemann tells MTV News the video for their second single goes back to 'hip-hop roots.'
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Tuesday 7 August 2012
Robert Plant And Alison Krauss Win Grammy Album Of The Year
Raising Sand, from Led Zeppelin vet and bluegrass superstar, wins five Grammys on Sunday night.
By James Montgomery with MTV News staff
<P>"I'm bewildered," <MTVNLINK type="artist" id="14245">Robert Plant</MTVNLINK> said onstage as he accepted the <MTVNLINK type="news" id="1604580">Grammy Album of the Year award</MTVNLINK> with <MTVNLINK type="artist" id="506074">Alison Krauss</MTVNLINK> on Sunday night. "In the old days we would have called this selling out, but it's a good way to spend a Sunday."</P><P>He was probably one of the few who were surprised, because <i>Raising Sand,</i> which won five trophies at Sunday night's show, is in many ways the perfect <a href="http://www.mtv.com/news/grammys/">Grammy</a> album. It features two respected veterans, a critically lauded producer, some sandpaper-and-velvet vocals and a baker's dozen of time-tested standards.</p><div style="margin: 0px 10px 10px 0px; float: left;"><embed src="http://media.mtvnservices.com/mgid:uma:video:mtv.com:338316" width="256" height="223" type="application/x-shockwave-flash" flashVars="configParams=instance%3Dnews%26vid%3D338316" allowFullScreen="true" allowScriptAccess="always" base="."></embed></div><p></P><P>You're probably familiar with Robert Plant from his <MTVNLINK type="artist" id="993">Led Zeppelin</MTVNLINK> days, and you might be aware of producer T-Bone Burnett's work on the "O Brother, Where Art Thou?" soundtrack (it won the Grammy for Album of the Year in 2002). And if you don't know who Alison Krauss is, she possesses a haunting set of pipes and is one of the meanest fiddle players in the world. Oh, and she's won 21 Grammys, more than any other female artist and the seventh-most in history.</P><P>Really, she's the key to <i>Sand</i>'s success, and not just because of her voice (or her fiddle playing). She and Plant first met in 2004, at a Rock and Roll Hall of Fame tribute to legendary bluesman Leadbelly, and the former Zeppelin man was amazed by her knowledge of American Roots music — so much so that they began kicking around the idea of recording an album together. Three years later, <i>Sand</i> was released.</P><P>And while Plant possesses the more famous voice, the album's finest moments radiate from Krauss. Whether she's getting bluesy on Little Milton's "Let Your Loss Be Your Lesson" or entwining with Plant's husky voice on songs like "Please Read the Letter" and Roly Salley's winsome "Killing the Blues," she more than carries her end of the bargain.</P><P>And perhaps that's also due to producer Burnett, who handpicked the 13 songs the duo cover on <i>Sand.</i> His arrangements are sparse — giving the two voices ample room to breathe — yet dense, warm and crackling at the same time. It's a testament to his work that he's often given just as much billing as Plant and Krauss on the project ... and it's certainly justified.</P><P>To date, <i>Sand</i> has sold more than 1 million copies, heaped tons of acclaim and actually earned a Grammy last year — "Gone Gone Gone (Done Moved On)" took home the award for Best Pop Collaboration With Vocals.</P><P>One expert was surprised not by the album's success, but by the fact that it's actually quite a good album.</P><P>"At first, the album seemed like a vanity project. ... Two names, clearly a one-off record, didn't have to be any good, you know?" <i>New York Times</i> music critic Jon Caramanica said. "Led Zeppelin fans would buy it because of Robert Plant, Alison Krauss would get a check. But it actually turned out to be a really thoughtful, really <i>good</i> record. So when you combine all that with the fact that the Grammys love to lionize one of their own, I could really see it taking home some awards." </P>
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Lady Gaga's ARTPOP: A History Of Album Title Oddities
From unpronounceable symbols to parentheses, Gaga's ALL-CAPS album title joins the ranks of the all-time weirdest.
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Photo: ChinaFotoPress/ Getty Images
Source:
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VIDEO: Tami Roman Talks “Basketball Wives” Controversy
“Basketball Wives” star Tami Roman address the controversy surrounding her reality show. Plus, find out what Tami’s daughters and boyfriend think about her behavior on the show.
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Britney Spears - Till the World Ends
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- Label: Jive
- Director: Ray Kay
- Album: Metamora
Source:
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Les News, 080712
• The first color images from Mars have been released. [Buzzfeed] • Taylor Swift wants to chat with you. [ONTD!] • Gwen Stefani and Gavin Rossdale get smoochy on the beach. [PopSugar] • Jennifer Lawrence may get $10 million for The Hunger Games: Catching Fire. [GossipCop] • Great Britain’s other diver Chris Mears is pretty [...]
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Mac Miller And Pharrell Writing Pink Slime's Last Chapter Together
Miller gave fans another taste of he and Pharrell's upcoming LP on Tuesday with their newest single, 'Glow.'
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Justin Bieber, Frank Ocean Win Gold In MTV's Summer Jam Games!
No Doubt, Ellie Goulding and Usher also join Biebs and Ocean on the summer song podium.
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Will Smith Inspires Tone Trump's New Fresh Prince Mixtape
'He inspired me a lot to turn my empire into a billion-dollar empire like he did,' Philly rapper tells Mixtape Daily.
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Justin Bieber Inspired By Michael Jackson For 'As Long As You Love Me' Clip
Singer tweets about the King of Pop's influence on his new video.
By Jocelyn Vena
<P>On Wednesday, <a href="http://www.mtv.com/music/artist/bieber_justin/artist.jhtml">Justin Bieber</a> dropped his cinematic clip for his track <a href="/news/articles/1690963/justin-bieber-as-long-as-you-love-me-music-video-premiere.jhtml">"As Long as You Love Me."</a> Heavy on drama and celebrity cameos, the video follows a lovelorn Bieber as he fights actor Michael Madsen for the right to hang out with his daughter, his one true love.</P><P><object width="460" height="260" type="application/x-shockwave-flash" id="embeddedPlayer" data="http://videoplayer.vevo.com/embed/embedded" style="visibility: visible;"><param name="bgcolor" value="#000000"><param name="allowFullScreen" value="true"><param name="allowScriptAccess" value="always"><param name="wmode" value="transparent"><param name="flashvars" value="playerType=embedded&videoId=USUV71201064&playlist=false&enableDomScan=true&siteSection=MTV_mtv.com&playerId=62FF0A5C-0D9E-4AC1-AF04-1D9E97EE3961&autoplay=0&endScreen=play&cc=US&cultureName=en-US&cultureIsRTL=False&sbId=14A00605-7DB5-4492-B67B-CB2093BD89DD"></object></P><P>In addition to the Baz Luhrmann-inspired Hawaiian shirts and "Romeo and Juliet" story line, Bieber takes a few punches and slings some sassy lines at Madsen. His pal Big Sean also makes an appearance in the clip. And if fans were wondering what and who influenced the video, Bieber took to <a href="https://twitter.com/justinbieber" target="_blank">Twitter</a> hours after the premiere to shout out his hero, Michael Jackson, for helping him step up his music-video game.</P><P>"MJ told stories with his videos. I wanted to tell a story. Feel like a movie. #AsLongAsYouLoveMe," he wrote, showing some love to the master. He later added, "Push the limits. Fight for what you BELIEVE in."</P><P>As of Wednesday night, Bieber was astounded that his video had amassed more than 1 million views in less than 10 hours. But that number nearly quadrupled on Thursday morning — as of press time, the video had almost 4 million streams.</P><P>Bieber is not only feeling the love for his <a href="/news/articles/1690932/justin-bieber-as-long-as-you-love-me-video.jhtml">"ALAYM" video</a> but also for his "Boyfriend" video, which just received two <a href="http://www.mtv.com/ontv/vma/2012/">2012 MTV Video Music Award</a> nominations for <a href="/news/articles/1690978/rihanna-only-girl-best-pop-video-video-music-awards.jhtml">Best Pop Video</a> and Best Male Video. Bieber goes into the September 6 broadcast already a two-time VMA winner. He'll learn if he can take home another one when the show goes live from the Staples Center.</P><P>The VMAs take place just weeks before Bieber kicks off his sold-out <a href="/news/articles/1688265/justin-bieber-after-believe.jhtml"><i>Believe</i> tour</a>, which coincidentally will also be heavily influenced by the King of Pop.</P><P>"He has been watching a tremendous amount of Michael Jackson concerts from the '80s and '90s," his manager Scooter Braun shared. "And he has been talking to me about how Michael incorporated magic and pyro and reveals and he wants to bring in that. [But] still do that acoustic thing, but he wants to take it to a whole new level.</P><P>"It's just really exciting," Braun continued. "Nothing makes him happier than being onstage. So it's gonna be fun to get back onto the road. I think he was an amazing performer before, but his level of dance and musicianship and his range [has grown]. He's a veteran now. I think he wants to take it to a completely new level."</P>
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